UNDATED (AP) — The 49ers' Patrick Willis is done for the rest of the season with a strained muscle in his left big toe that will require surgery. The seven-time Pro Bowl linebacker aggravated the injury in an Oct. 13 game against St. Louis. Willis missed the final 10 games of the regular season last year with the problem and has only played sporadically this season.

In other NFL news:

— Seattle defensive tackle Brandon Mebane will miss the rest of the season after suffering a hamstring injury in Sunday's win over the Giants. Fox Sports first reported that Mebane suffered a torn hamstring. Mebane's loss is a blow to Seattle's run defense, which ranks fourth in the league at 79.8 yards per game.

— Panthers coach Ron Rivera denies that there is anything physically wrong with quarterback Cam Newton who looked off his game in Monday night's loss to Philadelphia. Newton was sacked nine times and appeared to lack his usual mobility. Rivera has disputed published reports that Newton was injured. He says Newton, the doctors and trainers have told him they are unaware of any injury problem.

— The Jaguars placed rookie receiver Allen Robinson on injured reserve with a broken right foot. He initially hurt his foot against Miami on Oct. 26, and the pain kept getting worse. Tests Monday revealed a stress fracture. Robinson hasn't decided whether or not to have surgery. He has 48 receptions for 548 yards and two touchdowns.

— The Chicago Bears have waived former Super Bowl MVP receiver Santonio Holmes. He signed a one-year deal with Chicago in August after being released by the New York Jets in March. He had eight receptions for 67 yards along with nine punt returns for 50 yards.

— The New England Patriots still top the AP's Pro32 power rankings as voted on by a media panel that regularly covers the league. The 7-2 Patriots received seven of 12 first-place votes after enjoying a bye week. The 8-1 Arizona Cardinals received the other five first-place votes and stayed at No. 2 in the poll. The Denver Broncos, Philadelphia Eagles and Detroit Lions round out the top 5.

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